0 thank. I am a 53 yr old adult taking 20 mg of Vyvanse twice daily, spaced about 11 hours apart. I have taken General Psychology so I know a bit about how sleep and drugs work, so I'm thinking it's like, the drugs are keeping the brain too active to sleep properly. And it's a real problem for me. 40 years experience Allergy and Immunology. If you have any questions about this problem or any other risks of taking Vyvanse, talk to your doctor. Vyvanse stays in the system for up to 12 hours. Perhaps he can sleep around 3am if he has a tolerance to vyvanse. I've been on Vyvanse for over 8yrs and reached a plateau with my medication, until I drank coffee with my 50mg pill and I was up for like 24 hrs. The strength of Vyvanse wears off over time. You doesn't want to take that when the drugs effects are still potent. But about 4-5 hours after taking it, I feel like I need a nap. I take it now at 6 am and then go back to sleep until I wake up. I’ve had chronic migraines my whole adult life, but do not find that the Vyvanse has made them worse. Possible side effects are common for any prescription medication, and VyVanse is no exception. At first, I’d sleep 2 and 1/2 hours before waking, but now it is a half hour. It so far has been pretty good. This is a controlled substance, so doctors usually prescribe small doses. Anyway, I started on Vyvanse 30mg which is what I used to take and worked. At 8 hours in, the levels of Vyvanse are about 60% of their peak. In fact, I have fewer now than I used to have before Vyvanse. Vyvanse is a medication that doctors prescribe to treat attention deficit hyperactivity disorder or binge eating disorder. As for melatonin, most people think it is a natural sleeping pill. Sleep issues are a common side effect of stimulant medication. My first dose is around 3:30 -4:30 AM. VyVanse Side Effects and Sleep. Less common, but severe in nature, are vocal outbursts or uncontrollable body movements. Vyvanse is a medication prescribed for ADHD (attention deficit hyperactivity disorder). Vyvanse can be taken with or … 1 doctor agrees. Send thanks to the doctor. Vyvanse must be taken carefully to help prevent problems such as Vyvanse crash. 0. Might have to wait : Until the Vyvanse wears off to be able to sleep . It is a stimulant, which helps a person to concentrate. Should be able by tomorrow night . Dr. Al Hegab answered. Honestly, if You popped at 9:30, its very unlikely he will sleep by 1am. Drink coffee after taking your Vyvanse but not too much because you wont be able to sleep and if you're not healthy (over-weight) ask your dr first. I push through and end up okay but foggy for a while. Melatonin on its own won't induce sleep, and is usually only effective in short-term applications. At 13 hours in, they are at about 20% of their peak. I did sleep for 7 and a half hour. Common side effects are insomnia and irritability, but patients may also experience dizziness, weight loss, or even severe dry mouth. Vyvanse is taken as a once-daily oral medication in the morning. At 10 hours in, the levels are about 40% of their peak. My mind wanders and races; it can take me 3 hours to fall asleep. When I don't sleep well, I get out of breath easily, heart beats heavily, and feel dizzy. How To Intensify Vyvanse – What To Take, What To Do, A Guide Posted February 26, 2020 by Michael Chamberlain - See Editorial Guidelines. I have used benadryl to get to sleep after taking adderall, however that was long after having taken the adderall (xr). I barely notice the side effects and do notice I can start something and finish it without having to do 10 other things. Avoid afternoon or evening doses because it can interfere with sleep. I can do that. I've never been able to sleep well. So, trouble falling asleep may be even more pronounced with Vyvanse … The peak effects of dextroamphetamine from either the capsule or tablet formulation are reached in about 3.5 to 4.5 hours. 0 comment. 0. I’m retired.